IASO General Clinic has acquired Insightec’s Exablate Neuro^TM focused ultrasound device and offers a revolutionary treatment for neurological disorders, providing a bloodless alternative treatment with no craniotomy or anesthesia, unlike traditional surgical procedures used to treat Essential Tremor and Parkinson’s disease with severe tremor, which is unresponsive to medication.

At the core of Exablate Neuro^TM is the convergence of two powerful technologies: High-Intensity Focused Ultrasound (HIFU) guidance and Magnetic Resonance Imaging (MRI). Focused ultrasound is a rapidly evolving, minimally invasive therapeutic technology that can improve the quality of life of patients with Essential Tremor and Parkinson’s disease while reducing healthcare costs. This innovation focuses multiple ultrasound beams with maximum precision on areas deep within the brain. MRI guidance enables real-time imaging of the patient’s brain during the procedure. The high-resolution images provided by MRI allow the medical team to identify the targeted tissue with accuracy, monitor treatment progress during the ultrasound application, and make immediate adjustments, if necessary. This level of precision ensures that the surrounding healthy tissue remains unharmed, reducing the risk of complications.

The clinical risk of side effects for the patient is extremely low compared to other invasive treatment methods for movement disorders that require opening the skull and operating on the brain. The advantages of this treatment are numerous:

• Immediate symptom relief
• No craniotomy
• Reduced risk of infections, scarring and postoperative discomfort
• Real-time feedback
• Sub-millimeter target movement
• No penetrating trajectories with probes
• No implantable hardware
• No anesthesia
• Single-session procedure
• Short length of stay at the hospital and fast patient recovery.

The therapeutic procedure is carried out under the constant guidance of a neurologist, neuroradiologist, and neurosurgical team.

Mr. Ioannis Velentzas, Neurologist – Psychiatrist, Director of the 1^st Neurology Clinic & Neurophysiology Laboratory of IASO General Clinic, stated: “Insightec’s Exablate Neuro^TM method is changing the landscape. Patients who until now lived with severe tremor and limited functionality can now dramatically improve their daily lives, within just a few hours. The first five treatments have already been performed at IASO General Clinic with very positive results”.

Insightec’s Exablate Neuro^TM treatment platform is considered one of the most significant breakthroughs in neurology worldwide. By harnessing the power of focused ultrasound and MRI guidance, this technology offers a minimally invasive, absolutely precise, and safe alternative for treating conditions such as Essential Tremor and Parkinson’s disease, where tremor is the main symptom. As it significantly improves the quality of life of people affected by these disorders, Insightec’s Exablate Neuro™ represents great hope for patients and a testament to the remarkable progress of medical science.

IASO General Clinic, through its continued investment in technology and innovation, breaks new ground by offering patients access to the most advanced treatments available.

For more journalistic information: Nancy Christopoulou, Marketing, Communication & CSR Director, Commercial & Marketing Department, IASO Group, Tel: 210 6383917, E-mail: [email protected]