MD, PhD Director, Pediatric Opthalmology Department, IASO Pediatric Clinic
  1. Pediatric
  • Education & Academic Titles
    • 1996 – 2000 Bachelor of Arts in Biology, Magna Cum Laude
      Boston University, Boston MA
    • 2000 – 2004 Doctorate of Medicine
      Boston University School of Medicine, Boston MA
    • 2004 – 2005 Internship in Internal Medicine
      Caritas Carney Hospital, Boston MA
    • 2005 – 2008 Residency in Ophthalmology
      Boston University School of Medicine-Boston Medical Center, Boston MA
    • 2008 – 2009 Fellowship in Pediatric Ophthalmology and Adult Strabismus
      Harvard Medical School-Boston Children’s Hospital, Boston MA
    • 2009 – 2015 Instructor in Ophthalmology
      Harvard Medical School, Boston MA
    • 2016 – present Assistant Professor of Ophthalmology
      Harvard Medical School, Boston MA
  • Doctoral Thesis
    • 2018 Ophthalmic features of Progeria
      University of Patras Medical School
  • Professional Experience
    • 2022 – present Director, Pediatric Ophthalmology Department
      IASO Children’s Hospital
    • 2019 – present Telemedicine Consulting Staff, Department of
      Catholic Medical Center, Manchester NH
    • 2018 – 2019 Consultant Staff, Department of Pediatrics
      Baystate Medical Center, Springfield MA
    • 2012 – present Affiliate Attending, Department of Pediatrics
      South Shore Hospital, Weymouth MA
    • 2009 – present Consulting Physician, Department of Neonatology
      Beth Israel Deaconess Medical Center, Boston MA
    • 2009 – present Clinical Associate in Pediatrics, Department of Pediatrics
      Massachusetts General Hospital, Boston MA
    • 2009 – present Affiliate Attending, Department of Newborn Medicine
      Brigham and Women’s Hospital, Boston MA
    • 2009 – present Staff Physician, Pediatric Ophthalmology
      Massachusetts Eye and Ear Infirmary, Boston MA
    • 2008 – present Staff Physician, Department of Ophthalmology
      Boston Children’s Hospital, Boston MA
  • Clinical Interest
    • Pediatric strabismus
    • Adult strabismus
    • Retinopathy of prematurity
    • Pediatric cataract
    • Pediatric glaucoma
    • Pediatric ocular surface disease
  • Awards & Distinctions
    • 2003 Hygeia Scholarship
      New England Hellenic Medical and Dental Society
    • 2008 Farley Award
      Boston Children’s Hospital
    • 2010 Robert A. Petersen – Resident Teaching Award
      Department of Ophthalmology, Boston Children’s Hospital
    • 2015 Faculty Innovation Award
      Medical Staff Organization, Boston Children’s Hospital
    • 2015 Communication Award
      The Association for Research in Vision and Ophthalmology
    • 2015 Robert A. Petersen – Resident Teaching Award
      Department of Ophthalmology, Boston Children’s Hospital
    • 2015 Hecht Award
      New England Ophthalmologic Society
    • 2016 Best in Show Award
      American Association for Pediatric Ophthalmology and Strabismus
    • 2017 Robert A. Petersen – Resident Teaching Award
      Department of Ophthalmology, Boston Children’s Hospital
  • Recent Publications
    1. Dimitriou G, Greenough A, Mantagos JS, Davenport M, Nicolaides KH. Morbidity in infants with anterior abdominal wall defects. Pediatr Surg Int 2000; 16(5-6):404-7.
    2. Dimitriou G, Greenough A, Mantagos J, Skinner S. Metabolic acidosis, core-peripheral temperature difference and blood pressure response to albumin infusion in hypotensive, very premature infants. J Perinat Med 2001; 29:442-5.
    3. Mantagos IS, Rhodes J, Dagi LR. Transient monocular vision loss from acute rheumatic fever. Pediatr Cardiol 2008; 29:966-8.
    4. Mantagos IS, Vanderveen DK, Smith LH. Emerging treatments for retinopathy of prematurity. Semin Ophthalmol 2009;24:82-6.
    5. Heidary G, Löfqvist C, Mantagos IS, Vanderveen DK, Hellström A, Smith LE. Retinopathy of prematurity: clinical insights from molecular studies. Neo Reviews 2009; 10:e550-7.
    6. Huang JT, Mantagos J, Kapoor R, Schmidt B, Maguiness S. Langerhans cell histiocytosis mimicking molluscum contagiosum. J Am Acad Dermatol 2012; 67:e117-8.
    7. Ramasubramanian A, Mantagos I, Vanderveen DK. Corneal endothelial cell characteristics after pediatric cataract surgery. J Pediatric Ophthalmol Strabismus 2013;50:251-4.
    8. Mantagos IS, Vanderveen DK, Smith LEH. Risk factors for ROP: beyond age, birth weight, and oxygen. Curr Ophthalmol Rep 2013;1:213-7.
    9. Papakostas A, Jakobiec F, Mantagos J, Rashid A, Fay A, Vavvas D. Idiopathic dacryoadenitis mimicking a primary intraocular tumor in a young girl. Clin Experiment Ophthalmol 2014; 42:785-8.
    10. Thanos A, Mantagos IS. A 13-year old boy with asthma, itchy eyes, and decreased vision. J Pediatr 2014;165:1267.
    11. Shah AS, Prabhu SP, Sadiq MA, Mantagos IS, Hunter DG, Dagi LR. Adjustable nasal transposition of split lateral rectus muscle for third nerve palsy. JAMA Ophthalmol 2014;132:963-9.
    12. Talsania SD, Robson CD, Mantagos IS. Unilateral congenital lacrimal gland agenesis with contralateral lacrimal gland hypoplasia. J Pediatr Ophthalmol Strabismus 2015; 52:e52-4.
    13. Sadiq MAA, Corkin F, Mantagos IS. Eyelid lacerations due to dog bite in children. J Pediatr Ophthalmol Strabismus 2015;52:360-3.
    14. Saeed H, Mantagos IS, Chodosh J. Complications of Stevens-Johnson syndrome beyond the eye and skin. Burns 2016;42:20-7.
    15. Eldweik L, Mantagos IS. Role of VEGF inhibition in the treatment of retinopathy of prematurity. Semin Ophthalmol 2016;31(1-2):163-8.
    16. Kohanim S, Palioura S, Saeed HN, … Mantagos IS (17th/29 authors)…, Chodosh J. Stevens-Johnson syndrome/toxic epidermal necrolysis – A comprehensive review and guide to therapy. I. Systemic disease. Ocul Surf 2016;14:2-19.
    17. Ma K, Thanos A, Chodosh J, Shah AS, Mantagos IS. A novel technique for amniotic membrane transplantation in patients with acute Stevens-Johnson syndrome. Ocul Surf 2016;14:31-6.
    18. Kohanim S, Palioura S, Saeed HN, … Mantagos IS (17th/29 authors)…, Chodosh J. Stevens-Johnson syndrome/toxic epidermal necrolysis – A comprehensive review and guide to therapy. II. Ophthalmic disease. Ocul Surf 2016;14:168-88.
    19. Le HG, Saeed H, Mantagos IS, Mitchell CM, Goverman J, Chodosh J. Burn unit care of Stevens Johnson syndrome/toxic epidermal necrolysis: A survery. Burns 2016; 42:830-5.
    20. Ebrahimiadib N, Modjtahedi BS, Ferenchak K, Papakostas T, Mantagos JS, Vavvas DG. Optical coherence tomography findings and successful repair of retina detachment in Knobloch syndrome. Digit J Ophthalmol 2017;23(1):29-32.
    21. Wan MJ, Mantagos IS, Shah AS, Kazlas M, Hunter DG. Comparison of botulinum toxin with surgery for the treatment of acute-onset, comitant esotropia in children. Am J Ophthalmol 2017;176:33-9.
    22. Mantagos IS, Kleinman ME, Kierna MW, Gordon LB. Ophthalmologic features of Progeria. Am J Ophthalmol 2017;182:126-32.
    23. Wan MJ, Gilbert A, Kazlas M, Wu C, Mantagos IS, Hunter DG, Shah AS. The effect of botulinum toxin-augmentation on strabismus surgery for large-angle, infantile esotropia. Am J Ophthalmol 2018;189:160-5.
    24. Wallace DK, Dean TW, Hartnett ME, Kong L, Smith LE, Hubbard GB, McGregor ML, Jordan CO, Mantagos IS, Bell EF, Kraker RT; Pediatric Eye Disease Investigator Group. A dosing study of bevacizumab for retinopathy of prematurity: Late recurrences and additional treatments. Ophthalmology 2018;125:1961-6.
    25. Roohipoor R, Alvarez R, Brodowska K, … Mantagos IS, (15th/18 authors)…, Loewenstein J. Evaluation of computer-based retinopathy of prematurity (ROP) education for ophthalmology residents: a randomized, controlled, multicenter study. J AAPOS 2019;23:86.e1-86.e7.
    26. Oatts JT, Doyle JJ, Dodd MMU, Mantagos IS, Dagi LR. Acquired reversible Brown's syndrome caused by focal abscess of superior oblique muscle. JAAPOS 2019;23:172-4.
    27. Cheung CSY, Yang E, Robertson RL, Mantagos IS. Prenatal diagnosis of intraconal lymphatic malformation on fetal MRI. J AAPOS 2020;24:113-5.
    28. Gise R, Elhusseiny AM, Scelfo C, Mantagos IS. Mycoplasma pneumoniae induced rash and mucositis (MIRM): a longitudinal perspective and proposed management criteria. Am J Ophthalmol 2020;219:351-6.
    29. Bowe T, Hunter DG, Mantagos, IS et al. Virtual visits in ophthalmology: timely advice for implementation during the COVID-19 public health crisis. Telemed J E Health 2020;26:1113-7.
    30. Elhusseiny AM, Gise R, Mantagos IS. Trochleitis presenting with double vision in a patient with juvenile idiopathic arthritis. Orbit 2021;40:342-3.
    31. Gise R, Elhusseiny AM Scelfo C, Mantagos IS. Ocular involvement in recurrent infectious mucocutaneous eruption (RIME): a variation on a theme. J AAPOS 2021;25:62-4.
    32. Mantagos IS, Wu C, Griffith JF, et al. Retinopathy of prematurity screening and risk mitigation during the COVID-19 pandemic. J AAPOS 2021;25:91.e1-91.e5.
    33. Elhusseiny AM, Gise R, Scelfo C, Mantagos IS. Amniotic membrane transplantation in a 2-month-old infant with toxic epidermal necrolysis. Am J Ophthalmol Case Rep 2021; 21:101017.
    34. Scelfo C, Mantagos IS. Neurotrophic keratopathy in pediatric patients. Semin Ophthalmol 2021;36:289-95.
    35. Gjerde H, Mantagos IS.  Charting the globe: How technologies have affected our understanding of retinal findings in abusive head trauma/shaken baby syndrome. Semin Ophthalmol 2021;36:205-9.
    36. Elhusseiny AM, Bishop K, Staffa SJ, Zurakowski D, Hunter DG, Mantagos IS.  Virtual reality prototype for binocular therapy in older children and adults with amblyopia. J AAPOS 2021;25:217.e1-217.e6.
    37. Oke I, Mantagos IS.  Rates of unverifiable and incomplete publications in pediatric ophthalmology fellowship applications. J AAPOS 2021;25:295-7.
    38. Gotti G, Stevenson K, Kay-Green S, Blonquist TM, Mantagos JS, Silverman LB, Place AE. Ocular abnormalities at diagnosis and after the completion of treatment in children and adolescents with newly diagnosed acute lymphoblastic leukemia. Pediatr Blood Cancer 2022;69:e29542.
    39. Wiecek E, Akula J, Vanderveen DK, Mantagos IS, Wu C, Fulton A. Longitudinal change of refractive error in retinopathy of prematurity treated with intravitreal bevacizumab or laser photocoagulation. Am J Ophthalmol 2022;S0002-9394(22)00127-1.
    40. Tam EK, Elhusseiny AM, Shah AS, Mantagos IS, VanderVeen DK. Etiology and outcomes of childhood glaucoma at a tertiary referral center. J AAPOS 2022;S1091-8531(22)00064-7.
    41. Elhusseiny AM, Traish AS, Saeed HN, Mantagos IS. Topical cenegermin 0.002% for pediatric neurotrophic keratopathy. Eur J Ophthalmol 2022 [in print]
    42. Oke I, Heidary G, Mantagos IS, Shah AS, Hunter DG. Comparison of fellowship match opportunities and results across pediatric surgical subspecialities. J AAPOS 2022 [in print]
  • Membership in Societies and Editorial Boards
    • American Academy of Ophthalmology
    • American Association for Pediatric Ophthalmology and Strabismus
    • American Academy of Pediatrics
    • New England Ophthalmologic Society
    • Massachusetts Society of Eye Physicians and Surgeons
    • Massachusetts Medical Society
    • Hellenic Ophthalmological Society
    • Hellenic Association for Pediatric Ophthalmology and Strabismus
  • Research
    • Retinopathy of prematurity
    • Stevens Johnson syndrome
    • Strabismus
    • Amblyopia
    • Progeria